These Downsides have drastically minimized the cure solutions of chronic and intractable pain and so are mainly answerable for the current opioid disaster. Conolidine is generally effectively-tolerated, without major side effects noted. Any small effects that will manifest are generally moderate and common, for example slight stomach irritation or drowsiness. https://www.proleviate.com/post/what-are-the-side-effects-of-conolidine